The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, who are in serious danger of missin

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game

The Bills can clinch the division in Week 13 if the Miami Dolphins lose to the Green Bay Packers at Lambeau Field on Thursday Night Football and Buffalo defeats the San Francisco 49ers at Highmark Stadium on Sunday Night Football. Kickoff for both games is set for 8:20 p.m.

The Bills aren’t going to settle for just a playoff spot. They can clinch the AFC East in Week 13. Buffalo has nine wins to the Miami Dolphins’ five, but the Bills have the head-to-head tiebreaker over the Dolphins thanks to two wins. If both teams finish 9-7, Buffalo wins the tiebreaker.

The 2025 NFL playoffs don't start for another six weeks, but teams can start locking down a postseason berth as soon as this weekend. Three teams — the Buffalo Bills, defending champion Kansas City Chiefs and Detroit Lions — all have opportunities to clinch a spot in the postseason,

Kansas City Chiefs quarterback Patrick Mahomes has been fined more than $14,000 for pantomiming what the NFL deemed a "violent gesture" during a game last week against the Buffalo Bills.

The mindset, just first loss of the seat, just, you know, moving forward, right? And just tell motivated guys to just, yeah, I mean, it can, you can use it as fuel. Um, I mean, like I said, it's *** good football team so nothing to hang your head out,

The fine comes after the star quarterback celebrated a touchdown pass with a hand gesture that appeared to imitate him holding a gun.