Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an injury to his throwing shoulder.

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Here's what Samuel said about the

For the team's annual Feast with the Niners presented by Graton Casino event, the 49ers hosted low-income and transitional housing families for a meal, home resources and a shopping spree with players at Levi's® Stadium.

After the Green Bay Packers moved to 8-3, things are looking rosy as far as playoff qualification goes. Here's what to know.

The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park.

Head coach Kyle Shanahan explains why the 49ers don't rotate their running backs to give Christian McCaffrey a breather.

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look anywhere close to the player that he

He revealed he's been battling a fractured ankle throughout the season and gets injected with painkillers before every game.

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in Orchard Park, New York.