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Real Madrid has confirmed a second injury to a first team star which will likewise severely affect planning for a Champions League showdown with Manchester City.

Pep Guardiola will use this weekend's FA Cup tie at Leyton Orient to rotate with one eye on the seismic Champions League showdown with Real Madrid on Tuesday night. Manchester City are heavy favourites to progress against third tier Leyton Orient and will be keen to respond to their 5-1 thumping at Arsenal last time out.

Manchester City boss Pep Guardiola will probably make some changes with his side's Champions League tie against Real Madrid coming up on Tuesday, but he won't just field a load of kids. Instead it will probably be Kevin de Bruyne and Jack Grealish who come into the side,

Following today’s FA Cup tie against Leyton Orient, Manchester City have a host of tough fixtures awaiting them. Pep Guardiola’s side will face Real Madrid, Newcastle, Real Madrid again and