49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury during Sunday's 35-10 loss to the Buffalo Bills, and will be placed on injured reserve as result. McCaffrey's recovery is expected to be six weeks, meaning that the rest of his season is in jeopardy.

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San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach Kyle Shanahan told

Christian McCaffrey may be done for the rest of 2024. Following Sunday’s 35-10 loss to the Bills, 49ers head coach Kyle Shanahan told reporters in his postgame press conference that McCaffrey suffered a PCL injury that could be season-ending.

Christian McCaffrey's season might be over as he, along with backup running back Jordan Mason, will be placed on injured reserve.

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back exited Sunday’s snowy game in Buffalo with a non-contact injury.

McCaffrey suffered a potentially season-ending PCL injury, 49ers coach Kyle Shanahan said after the 35-10 loss to the Bills. McCaffrey took a toss, limped a couple steps and slid to the ground to give himself up for a 5-yard loss. He got to his feet and gingerly jogged off the field and into the blue medical tent.

The 49ers running back went down with a non-contact knee injury early in San Francisco's 35-10 loss to the Buffalo Bills on Sunday night. Head coach Kyle Shanahan said after the game at Highmark Stadium that McCaffrey sustained a "potentially" season-ending PCL injury. Further specifics are not yet known.

Christian McCaffrey Heading to IR With PCL Injury