The 49ers are getting desperate at running back after three injuries. Here’s who is next up in Kyle Shanahan’s offense.

Stafford is arguably the best quarterback in the NFL when he can operate from a clean pocket — he’s thrown for 2,656 yards ...

Derrick Feldt, a 49ers fan who has beaten cancer twice, caught the attention of San Francisco star Christian McCaffrey before the Week 13 game in Buffalo and received a special gift.

But Sunday was also the first game the Niners used Guerendo, their fourth-round pick in the 2024 draft and the fourth running ...

With the Commanders suffering an injury at wide receiver, it's time for these two players to step up and the team looks to ...

As Israel steps up its airstrikes against Syria, Israel's Defense Minster says he's ordered the IDF to establish a "sterile ...

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

Iowa Hawkeyes running back Kaleb Johnson has declared for the 2025 NFL Draft, which does not come as much of a surprise based ...

The San Francisco 49ers didn't anticipate getting down to a fourth-string running back, but they may find themselves in that ...

More and more you could make an argument the most dangerous job is that of running back for the San Francisco 49ers.

San Francisco 49ers running back Christian McCaffrey is opening up after suffering a likely season-ending knee injury in the ...