Ashley Anders, of Center City, can’t remember missing a Thanksgiving Day parade in her entire 49 years. She also can’t remember a Thanksgiving Day when it rained during the entire event. She’s attended when it has been 80 degrees and when it was freezing — but never when it was raining.

Philadelphia residents should expect road closures for the annual Thanksgiving Day Parade. Here's what you need to know.

The oldest Thanksgiving Day parade in the nation marches through Center City and up the Ben Franklin Parkway to the Philadelphia Museum of Art.