The EMBO Journal4d
A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor
Chronic nitric oxide (NO) donor treatment is a novel antiepileptic strategy that has an effect beyond neuronal ion channels.
The EMBO Journal10d
Targeting to BMP9 to restrain flare-up of fibrodysplasia ossificans progressiva
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized primarily by the formation of heterotopic ...
The EMBO Journal9d
Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Retinoic acid (RA) signaling is a master ...
The EMBO Journal2d
The TRIM37 variant rs57141087 contributes to triple-negative breast cancer outcomes in Black women
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The risk variant rs57141087 is predominant in ...
The EMBO Journal24d
ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The class-II transactivator (CIITA) is the ...
The EMBO Journal18d
Gpr54 deletion accelerates hair cycle and hair regeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. GPR54, or KiSS-1R (Kisspeptin receptor), is ...
The EMBO Journal8d
Histone methyltransferases MLL2 and SETD1A/B play distinct roles in H3K4me3 deposition during the transition from totipotency to pluripotency
In early mammalian embryogenesis, a shift from non-canonical histone H3 lysine 4 trimethylation (H3K4me3) linked to transcriptional repression to canonical H3K4me3 indicating active promoters occurs ...
The EMBO Journal11d
Flagellar rotation facilitates the transfer of a bacterial conjugative plasmid
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Conjugation-mediated DNA delivery is the ...
The EMBO Journal11d
Mechanisms of axoneme and centriole elimination in Naegleria gruberi
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The early branching eukaryote Naegleria ...
The EMBO Journal14d
Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromatin remodeling is likely to be required ...
The EMBO Journal9d
How J-chain ensures the assembly of immunoglobulin IgM pentamers
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Polymeric IgM immunoglobulins have high ...
The EMBO Journal15d
The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The immunoregulatory cytokine TGF-β is ...