Since training camp, the 49ers season hasn't gone as planned amid injuries to star players and on-field struggles.

San Francisco 49ers rookie running back Isaac Guerendo is dealing with a foot injury and is listed as questionable for Week 15 against the Los Angeles Rams on T ...

The 49ers are getting desperate at running back after three injuries. Here’s who is next up in Kyle Shanahan’s offense.

Stafford is arguably the best quarterback in the NFL when he can operate from a clean pocket — he’s thrown for 2,656 yards ...

Derrick Feldt, a 49ers fan who has beaten cancer twice, caught the attention of San Francisco star Christian McCaffrey before the Week 13 game in Buffalo and received a special gift.

Lattimore is trending toward making his Commanders debut at the Saints, while Brown is out long term Marshon Lattimore is trending in the right direction to play Sunday after missing time with a ...

But Sunday was also the first game the Niners used Guerendo, their fourth-round pick in the 2024 draft and the fourth running ...

With the Commanders suffering an injury at wide receiver, it's time for these two players to step up and the team looks to secure a playoff berth.

As Israel steps up its airstrikes against Syria, Israel's Defense Minster says he's ordered the IDF to establish a "sterile ...

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

The 49ers got a big win in Week 14 but Deebo Samuel continues to be an afterthought on offense, causing frustration for the wideout.