Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

McCaffrey was initially said to be out at least six weeks — with five weeks left in the season. Niners head coach Kyle ...

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

San Francisco 49ers running back Christian McCaffrey has spoken out after being placed on injured reserve with yet another ...

The 28-year-old took to social media on Wednesday to share a heartfelt message for 49ers fans after his injury-plagued ...

Taking to social media to address the situation head-on, McCaffrey delivered a bittersweet statement to his fans on Instagram ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

McCaffrey's post garnered all sorts of reactions from fans and NFL personalities alike. One that stood out, however, is his wife Olivia Culpo's five-word message for her husband, who is clearly going ...

Head coach Kyle Shanahan reflected on the team's performance against the Bills, previewed the upcoming Week 14 matchup ...

Isaac Guerendo will make his first NFL start on Sunday as the injury-depleted San Francisco 49ers face the Chicago Bears. The ...

On Sunday night against the Buffalo Bills, star running back Christian McCaffrey suffered a knee injury that may cost him the ...